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Before using Baclofen (Lioresal), tell your health care professional if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Baclofen. This list is not complete and other drugs may interact with Baclofen (Gablofen). Tell your doctor about all medications you use.

Usual Adult dose of Baclofen (Gablofen) for Trigeminal Neuralgia: Oral: Initial dose: 5 mg orally 3 times a day for 3 days, then 10 mg orally 3 times a day for 3 days, then 15 mg orally 3 times a day for 3 days, then 20 mg orally 3 times a day. Maintenance dose: 40-80 mg/day. 80 mg/day dosages should be administered in 4 divided dosages.

Baclofen (Lioresal) has been assigned to pregnancy category C by the FDA. Animal studies have revealed an increased incidence of omphaloceles. There are no controlled data in human pregnancy. Baclofen should only be given during pregnancy when benefit outweighs risk.

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Baclofen (Intrathecal) for Muscle Spasm: Have been put on Baclofen (Intrathecal) for spasms in legs and back after back fusion for injury due to train crash. The benefit has been enormous. I can now sleep, walk and lead an almost normal life. I only take 5mg three times a day.

Prescribed for the cervical myalgia and muscle spasms in my neck associated with migraine; can feel it "melting" the spasms. Side effects minimal at my 5 - 10 mg doses. Very helpful.

Baclofen (Intrathecal) for Migraine Prevention: I have had migraines for 6 years and have tried every medication from, Topamax to Zonegran to Depakote. Since I've started taking Baclofen (Gablofen) 20mg x 3 times daily, 6 months ago, I have had one breakthrough headache and even then I was able to function. I'm not saying Baclofen (Intrathecal) is the "perfect migraine prevention medicine" but for me, it's been my miracle pill.

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Publilius Syrus: Good health and good sense are two of life's greatest blessings.

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Baclofen Oncologic side effects including carcinoma have been reported. Baclofen Musculoskeletal side effects including ataxia and muscle pain have been reported. Baclofen (Gablofen) Hematologic side effects including leukocytosis and petechial rash have been reported.

Baclofen (Gablofen) Side Effects - The most common is transient drowsiness (10–63%). In one controlled study of 175 patients, transient drowsiness was observed in 63% of those receiving Baclofen (Gablofen) compared to 36% of those in the placebo group. Other common adverse reactions are dizziness (5–15%), weakness (5–15%) and fatigue (2–4%).

Store Baclofen (Gablofen) at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly closed container. Brief periods at temperatures of 59 to 86 degrees F (15 to 30 degrees C) are permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Baclofen (Lioresal) out of the reach of children and away from pets.

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Baclofen for Muscle Spasm: I have been suffering from a dull and persistent pain on the right side of my abdomen near my rib cage for several months. I had blood tests and abdominal ultrasound with results indicating "normal" appearance. The pain persisted and I could control it to some extent (not great) with Tylenol extra strength. Then I asked my healthcare professional to prescribe 10mg Baclofen (Intrathecal), which I have been taking 3 times daily for about two weeks. I noticed my abdominal pain eased after 2 days of the medication. I haven't been experiencing abdominal pain except on rare occasion since I have been taking Baclofen (Gablofen). I feel totally functional and thankful that I don't have to live in pain any longer.

Baclofen (Lioresal) for Muscle Spasm: Baclofen (Lioresal) is so good! Some drowsiness, although could be from Lyrica, which I stopped today due to my new Fred Flintstone feet (Side effect from Lyrica - needed Ultrasound to rule out DVT - clots in leg). Okay for pain after short buildup period, but after that period I started getting MOST of the listed side effects of Lyrica - including the ER visit with the swollen feet). I had spinal surgery and now suffer SEVERE back spasms. (I'm worse off after surgery). I now have MORE nerve pain - so hence the Lyrica - and really bad spasms when I stand for short periods or lay in one position and Baclofen (Gablofen) is a God send.

Baclofen (Gablofen) for Periodic Limb Movement Disorder: I've had MS for 25 years and suffer more with fatigue than anything else, but at night when I was over tired I would get twitchy and had terrible restless legs. I now take 10mg of Baclofen each night and sleep soundly. I wake up feeling refreshed, something that I've not felt for a very long time so I recommend this medication.

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