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Baclofen (Lioresal) Side Effects Neuropsychiatric: Confusion (1–11%), headache (4–8%), insomnia (2–7%); and, rarely, euphoria, excitement, depression, hallucinations, paresthesia, muscle pain, tinnitus, slurred speech, coordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizure.

Baclofen (Gablofen) Side Effects - The most common is transient drowsiness (10–63%). In one controlled study of 175 patients, transient drowsiness was observed in 63% of those receiving Baclofen (Lioresal Intrathecal) compared to 36% of those in the placebo group. Other common adverse reactions are dizziness (5–15%), weakness (5–15%) and fatigue (2–4%).

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dosage.

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Baclofen (Gablofen) for Muscle Spasm: I have been struggling with fibromyalgia for more than five years. Finally accepted my diagnoses almost 3 years ago. My healthcare professional and I have been working together to establish a pain management program that works for me and still enables me to work and live a "normal" life. Baclofen (Gablofen) is by far the best muscle relaxer I have used and true to my doctors recommendation, has the least side effects (dizziness, sedation, etc.). I am more than just pleased with this medicine. I am THRILLED because it helps to control the muscle spasms I cope with while allowing me to be an active participant in my life. After two years of taking it, I am taking 10mg four times a day.

Baclofen (Lioresal) for Muscle Twitching: I was prescribed Baclofen 5 years ago for BFS and chronic fatigue. Helped a great deal with the fatigue, but didn't stop the fasciculations in my legs and feet. I'm still taking 5mg, three or four times a day.

Baclofen (Lioresal) for Periodic Limb Movement Disorder: I've had MS for 25 years and suffer more with fatigue than anything else, but at night when I was over tired I would get twitchy and had terrible restless legs. I now take 10mg of Baclofen (Gablofen) each night and sleep soundly. I wake up feeling refreshed, something that I've not felt for a very long time so I recommend this medication.

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Leon Eldred: If I'd known I was going to live so long, I'd have taken better care of myself.

Plato: Attention to health is life's greatest hindrance.

January Jones: I lived in a town of 400 until I was like nine or ten. My dad coached all the sports - he was a gym teacher and health teacher for grades K-12.

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Baclofen (Lioresal) Other effects including fever, malaise, hypothermia, slurred speech, nightmares, confusion, headache, memory impairment, insomnia, and excitement have been reported. Baclofen Hepatic side effects including elevated liver function tests have been reported rarely.

Baclofen Side Effects Gastrointestinal: Nausea (4–12%), constipation (2–6%); and, rarely, dry mouth, anorexia, taste disorder, abdominal pain, vomiting, diarrhea, and positive test for occult blood in stool.

Baclofen (Lioresal Intrathecal) General side effects have included effects on sleep. One study has reported that a single, therapeutic dosage of Baclofen alters sleep architecture and produces a small reduction in mean sleep oxygen saturation, but does not significantly increase sleep disordered breathing.

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Baclofen (Lioresal) for Alcohol Withdrawal: Wow! Is the only word to describe my experience to date. I have read the side effects but my experiences have been very benign. I have had no thoughts of drinking after a multi month period of increasing usage. My side effects have been an increase in self esteem, better sleep (although my sleep cycle has changed and I actually sleep less but have deeper more restful sleep) waking more refreshed, better mood, focus and clarity. I don't see many of these mood altering properties listed in side effects but they are real experiences for me.

Baclofen (Lioresal) for Muscle Spasm: I have tried many spasm medications since 2002 for major muscle spasms. I was in a car accident and now I'm left with very bad uncontrollable spasms. This is the only one that worked, but after 6 years of taking it, it doesn't work anymore but for short term usage of this medication it works very well

Prescribed for the cervical myalgia and muscle spasms in my neck associated with migraine; can feel it "melting" the spasms. Side effects minimal at my 5 - 10 mg doses. Very helpful.

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