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Baclofen has been assigned to pregnancy category C by the FDA. Animal studies have revealed an increased incidence of omphaloceles. There are no controlled data in human pregnancy. Baclofen (Lioresal) should only be given during pregnancy when benefit outweighs risk.
Baclofen Side Effects - The most common is transient drowsiness (10–63%). In one controlled study of 175 patients, transient drowsiness was observed in 63% of those receiving Baclofen (Lioresal) compared to 36% of those in the placebo group. Other common adverse reactions are dizziness (5–15%), weakness (5–15%) and fatigue (2–4%).
Usual Adult dose of Baclofen (Lioresal) for Muscle Spasm: Oral: Initial dosage: 5 mg orally 3 times a day for 3 days, then 10 mg orally 3 times a day for 3 days, then 15 mg orally 3 times a day for 3 days, then 20 mg orally 3 times a day. Maintenance dosage: 40-80 mg/day. 80 mg/day dosages should be administered in 4 divided dosages.
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Baclofen for Muscle Spasm: I have been taking Baclofen (Gablofen) for a couple of months now for severe muscle spasms. Not only does it help those muscle spasms, but I have borderline personality disorder, and this medication has given me a sense of well-being. I also have severe anxiety, I find when I take the Baclofen (Lioresal), (80 mgs a day) I do not feel anxious, nor do I have anxiety attacks. I believe more research needs to be done on this drug about its effects on different types of mental illness.
Baclofen (Lioresal) for Muscle Twitching: I was prescribed Baclofen (Gablofen) 5 years ago for BFS and chronic fatigue. Helped a great deal with the fatigue, but didn't stop the fasciculations in my legs and feet. I'm still taking 5mg, three or four times a day.
Baclofen (Intrathecal) for Spasticity: This drug works. If I am late with a dose or miss a dose I feel it. I can't go through the day without it.
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Also if you're not sick of reading - here are several in some way funny expressions about health and medications from some well known men and women:
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Malcolm Fraser: Over 120 Aboriginal communities run their own health services - some have been doing so for 30 years. They struggle with difficult medical problems. They also try to deal with counselling, stolen generations issues, family relationships, violence, suicide prevention.
Herbert Spencer: The preservation of health is a duty. Few seem conscious that there is such a thing as physical morality.
William Temple: You may keep your beauty and your health, unless you destroy them yourself, or discourage them to stay with you, by using them ill.
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FDA pregnancy category C. It is not known whether Baclofen (Lioresal Intrathecal) will harm an unborn baby. Tell your health care professional if you are pregnant or plan to become pregnant while using this medication. It is not known whether Baclofen (Lioresal) passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using Baclofen (Lioresal Intrathecal). Do not give this medication to a child younger than 12 years old. Older adults may be more sensitive to the effects of this medicine.
If you become pregnant, contact your healthcare professional. You will need to discuss the benefits and risks of using Baclofen (Gablofen) during while you are pregnant. It is not known if Baclofen (Lioresal) is found in breast milk. Do not breast-feed while taking Baclofen (Lioresal).
Baclofen Gastrointestinal side effects including nausea, vomiting, constipation, abdominal pain, diarrhea, dysphagia, fecal incontinence, gastrointestinal hemorrhage, and tongue disorder have been reported (especially with rapid dosage increases).
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Baclofen for Muscle Spasm: Was given this medication post hysteroscopy when I suffered severe hip, knee and leg pain. Nothing touched it. Had major painkillers to no effect. Baclofen (Lioresal) was a lifesaver. Also have fibromyalgia and the bonus is I can feel a massive difference with that now as well. Am a bit dizzy, hope it will pass in time cause the benefits are worth it! No other side effects at all.
Baclofen (Lioresal) for Muscle Spasm: I have suffered with back pain and muscle spasms for almost ten years. Sleeping through the night only happened in my dreams. Travel was limited by the necessity to stop frequently, get out and walk/stretch. A 200 mile trip could take 6 hours. Hotel beds were excruciating. After three weeks of routine dosing, my dreams are now a reality. Sleeping thru the night, driving for extended periods and staying away from home overnight have given me my life back.
I Was diagnosed with a herniated L4 three years ago and had just recently had a flare up of spasms in my lower and mid back. In the past the health care professional has prescribed Flexoril and Robaxin for my muscle pain/spasms and it worked poorly. Now that i have been prescribed Baclofen (Gablofen), i have had great results. Have had the best sleep in months due to the help with this drug.
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